The Genetic Basis of Human Cancer

Advances in the fields of genetics and molecular biology have made a great impact in oncology and cancer research. This book aims to present a thorough review of the fundamentals of genetics and human phenotypes, gene mutation, the Human Genome Project and genetic imprinting. From relatively rare to massively prevalent oncologic diseases and syndromes, the authors cover topics from melanoma, breast cancer and prostate cancer to Wilms Tumour. The chapter organization reflects clinical aspects; genetic loci, specific genes and implications for diagnosis.